This project will identify the available evidence on biological and physiological markers of multimorbidity in adults.
Knowledge Exchange Projects
We believe that science is not driven by great ideas alone, but also by networks of people that are committed to delivering impact from these ideas. These projects enable people to workacross the ageing innovation space to exchange knowledge. This includes the pharmaceutical industry, SMEs, VCs, academia, the NHS, patient groupsand spans academic fields including biomedicine, law, and economics.
Global Access to Medicines
Project lead:
Harriet Teare, University of Oxford
We have provided funding to support the development of a web platform and run a workshop to enable knowledge exchange on the economic, political, practical and ethical challenges associated with access to medicines.
Committed Philanthropy
Project lead:
Heather Draper, University of Warwick
This project investigates the feasibility of adopting a new approach to funding clinical trials through committed philanthropy, a process where a trial is funded by donors, who wish to be part of the trail themselves.
Drug Discovery in Ageing
Project lead:
Janet Lord, University of Birmingham
This project will review the current literature on age-related multimorbidity clusters and the biological processes driving such clusters. It will assess the evidence for new drugs targeting age-related mechanisms and propose clinical trial methodology to test such drugs.
Priority Setting for Clinical Adoption
Project lead:
Duncan Richards, University of Oxford
We will support a pair of multi-disciplinary knowledge exchange workshops using the STAR (Socio-Technical Allocation of Resource) method. These workshops will assess how to prioritise implementation of novel medical interventions.
Efficient Lung Drug Delivery Systems
Project lead:
Esra Sorguven, University of Sussex
This project will explore the use of electronic delivery devices for the efficient delivery of pharmaceuticals to lung tissue.
Comprehensive and collaborative screening of small molecule inhibitors across a range of disease-specific assays in ageing and inflammation (including COVID-19)
Project lead:
Cassandra Adams, Centre for Medicines Discovery, University of Oxford
A comprehensive translational screening project across an extensive network of collaborators with specific expertise in ageing and senescence, utilising the SGC compound library of > 60 unique small molecules, selective for novel epigenetic targets.
Pharmaco-epidemiology for discovery of targets and modulating strategies to protect against age-related macular degeneration
Project lead:
Wen Hwa Lee, Action Against Age-related Macular Degeneration (AAAMD)
The goal of this project is to investigate whether there are medications in current use which are associated with reduced or increased risk of AMD.